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Language Mapping in Multilingual Patients: Electrocorticography and Cortical Stimulation During Naming
- Source :
- Frontiers in Human Neuroscience, Vol 5 (2011), Frontiers in Human Neuroscience
- Publication Year :
- 2011
- Publisher :
- Frontiers Media SA, 2011.
-
Abstract
- Multilingual patients pose a unique challenge when planning epilepsy surgery near language cortex because the cortical representations of each language may be distinct. These distinctions may not be evident with routine electrocortical stimulation mapping (ESM). Electrocorticography (ECoG) has recently been used to detect task-related spectral perturbations associated with functional brain activation. We hypothesized that using broadband high gamma augmentation (HGA, 60-150 Hertz) as an index of cortical activation, ECoG would complement ESM in discriminating the cortical representations of first (L1) and second (L2) languages. We studied four adult patients for whom English was a second language, in whom subdural electrodes (a total of 358) were implanted to guide epilepsy surgery. Patients underwent ECoG recordings and electrocortical stimulation mapping (ESM) while performing the same visual object naming task in L1 and L2. In three of four patients, ECoG found sites activated during naming in one language but not the other. These language-specific sites were not identified using ESM. In addition, ECoG HGA was observed at more sites during L2 versus L1 naming in two patients, suggesting that L2 processing required additional cortical resources compared to L1 processing in these individuals. Post-operative language deficits were identified in three patients (one in L2 only). These deficits were predicted by ECoG spectral mapping but not by ESM. These results suggest that pre-surgical mapping should include evaluation of all utilized languages to avoid post-operative functional deficits. Finally, this study suggests that ECoG spectral mapping may potentially complement the results of ESM of language.
- Subjects :
- Electrocortical Stimulation Mapping
naming
Stimulation
high gamma
Language mapping
050105 experimental psychology
lcsh:RC321-571
03 medical and health sciences
Functional brain
Behavioral Neuroscience
0302 clinical medicine
Spectral mapping
Cortex (anatomy)
medicine
0501 psychology and cognitive sciences
Epilepsy surgery
Electrocorticography
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
neoplasms
Biological Psychiatry
Original Research
electrocorticography
medicine.diagnostic_test
electrocortical stimulation mapping
05 social sciences
functional mapping
ECoG
Psychiatry and Mental health
medicine.anatomical_structure
Neuropsychology and Physiological Psychology
Neurology
epilepsy surgery
multilingual
Psychology
Neuroscience
030217 neurology & neurosurgery
Subjects
Details
- Language :
- English
- ISSN :
- 16625161
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Frontiers in Human Neuroscience
- Accession number :
- edsair.doi.dedup.....52ed8e447f5ef6190662ccdb6fe837bd
- Full Text :
- https://doi.org/10.3389/fnhum.2011.00013