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Decoupled fluorescence Monte Carlo model for direct computation of fluorescence in turbid media
- Source :
- Journal of biomedical optics. 20(2)
- Publication Year :
- 2014
-
Abstract
- We present a decoupled fluorescence Monte Carlo (dfMC) model for the direct computation of the fluorescence in turbid media. By decoupling the excitation-to-emission conversion and transport process of the fluorescence from the path probability density function and associating the corresponding parameters involving the fluorescence process with the weight function, the dfMC model employs the path histories of the excitation photons and the corresponding new weight function to directly calculate the fluorescence. We verify the model’s accuracy using phantom experiments and compare it with that of the perturbation fluorescence Monte Carlo model. The results indicate that the model is accurate for the direct fluorescence calculation and, thus, has great potential for application in fluorescence-based in vivo tomography.
- Subjects :
- Physics
Weight function
Photon
business.industry
Phantoms, Imaging
Monte Carlo method
Optical Imaging
Biomedical Engineering
Reproducibility of Results
Probability density function
Fluorescence correlation spectroscopy
Fluorescence
Atomic and Molecular Physics, and Optics
Imaging phantom
Electronic, Optical and Magnetic Materials
Computational physics
Biomaterials
Optics
Spectrometry, Fluorescence
Nephelometry and Turbidimetry
Direct methods
Scattering, Radiation
Computer Simulation
business
Monte Carlo Method
Subjects
Details
- ISSN :
- 15602281
- Volume :
- 20
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of biomedical optics
- Accession number :
- edsair.doi.dedup.....52e438485412741d9d120aeae735a13b