Additional file 5 of Cerebrospinal fluid A beta 1–40 peptides increase in Alzheimer’s disease and are highly correlated with phospho-tau in control individuals

Additional file 5 : Sup-Figure 3. Aβ40 in different clinical groups. The Montpellier, Paris and SPIN-Barcelona cohorts displayed a large range of pathological samples from patients with Alzheimer’s disease (AD), cerebral amyloid angiopathy (CAA), frontotemporal degeneration (FTD), mild cognitive impairment (MCI), normal pressure hydrocephalus (NPH), vascular dementia (VASC), other neurological diseases (amytrophic lateral sclerosis, Parkinson’s disease, Lewy Body dementia..) (Other) and control (subjective cognitive impairment). Box plots with median and 25th/75th percentile of CSF Aβ40 values are plotted for the four cohorts (panels A-D). Note that the distribution of the diagnoses differ in the cohorts (see Methods). Non parametric Mann–Whitney U test were performed between the AD and the other clinical groups. P values below statistical significance are in red.