Is There a Role for Cervicography in the Detection of Premalignant Lesions of the Uterine Cervix?

OBJECTIVE This study aimed to compare cervical cancer screening by cervicography with screening by Pap test. MATERIALS AND METHODS This was a comparative multicenter study of cervical cytology and cervicography. The cervicography (slides of the cervix) was taken after the Pap test was completed. In total, samples were collected from 1176 patients. Colposcopy with biopsy was considered the gold standard for the final diagnosis of lesions observed by the Pap test and cervicography. Statistical analysis was performed using the binomial test. RESULTS In cases in which the Pap test was negative for cervical lesions, diagnosis by cervicography was positive in 15 cases of cervical intraepithelial neoplasia 1 (CIN 1) (p = .00052), in 1 case of CIN 2, in 1 case of CIN 3, and in 1 case of cancer. However, cervicography produced 3 false-positive results (p < .0001). CONCLUSIONS Cervicography may be used as a complementary screening method to the Pap test for cervical cancer.