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A nationwide analysis on the influence of obesity in inflammatory bowel disease hospitalizations

Authors :
Dhanshree Solanki
Hafeez Shaka
Farah Wani
Asim Kichloo
Jagmeet P. Singh
Dushyant Singh Dahiya
Source :
Intestinal Research. 20:342-349
Publication Year :
2022
Publisher :
Korean Association for the Study of Intestinal Diseases, 2022.

Abstract

Background/Aims: Proinflammatory cytokines released from adipocytes can influence the development, progression, and treatment of inflammatory bowel disease (IBD), and may be associated with worse clinical outcomes. Methods: For 2016–2018, we analyzed data from the Nationwide Inpatient Sample to identify adult (≥18 years) hospitalizations with a primary discharge diagnosis of IBD. The study sample was divided based on the presence or absence of obesity. The primary outcomes included inpatient mortality, while the secondary outcomes consisted of system-based complications and disease implications on the United States healthcare system.Results: We identified 282,005 hospitalizations of IBD from 2016 to 2018. Of these hospitalizations, 26,465 (9.4%) had a secondary diagnosis of obesity while 255,540 (90.6%) served as controls. IBD hospitalizations with obesity had a higher mean age (47.9 years vs. 45.2 years, PPPPP

Details

ISSN :
22881956 and 15989100
Volume :
20
Database :
OpenAIRE
Journal :
Intestinal Research
Accession number :
edsair.doi.dedup.....52bf02e301b5d545a392424db4c064d9