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Bilateral versus unilateral thyroid eye disease
- Source :
- Indian Journal of Ophthalmology, Vol 59, Iss 5, Pp 363-366 (2011), Indian Journal of Ophthalmology
- Publication Year :
- 2011
- Publisher :
- Wolters Kluwer Medknow Publications, 2011.
-
Abstract
- Aims: The aim of this study was to compare demographics, clinical manifestations, associated systemic and ocular factors, severity and activity of patients with unilateral thyroid eye disease (U-TED) versus bilateral thyroid eye disease (B-TED). Materials and Methods: In a cross-sectional study, all patients with Graves' hyperthyroidism and primary hypothyroidism seen in an endocrinology clinic were included from September 2003 to July 2006. Demographics, complete eye examination, severity score (NOSPECS, total eye score), and clinical activity score were recorded and compared in the B-TED and U-TED groups of patients. Results: From 851 patients with thyroid disorders, 303 (35.6%) had TED. Thirty-two patients (32/ 303, 10.56%) were found to have U-TED. Patients with U-TED (mean age 31.6 ± 11.6 years) were significantly younger than patients with B-TED (mean age 37.7 ± 14.7 years). Monovariate analysis (Chi-square and independent sample t-test) showed a significantly higher severity score in B-TED (U-TED 4.09±4.05, B-TED: 6.7±6.3; P= 0.002) and more activity score in B-TED (U-TED= 1.03±0.96, B-TED: 1.74±1.6, P= 0.001). However, multivariate analysis did not show any significant difference between the two groups in terms of age, gender, type of thyroid disease, duration of thyroid disease and TED, severity and activity of TED, smoking habit, and presentation of TED before or after the presentation of thyroid disease (0.1
- Subjects :
- Male
Cross-sectional study
analysis
Eye disease
Visual Acuity
Diagnostic Techniques, Ophthalmological
Iran
Severity of Illness Index
Behcet′s disease
Graves′ ophthalmopathy
lcsh:Ophthalmology
Graves’ ophthalmopathy
Child
Aged, 80 and over
medicine.diagnostic_test
Incidence
Thyroid disease
Thyroid
Primary hypothyroidism
Middle Aged
Prognosis
Pediatric traumatic cataract
medicine.anatomical_structure
Eye examination
Female
Original Article
square-edge intraocular lens
Adult
medicine.medical_specialty
Adolescent
posterior capsule opacification
HLA-B51
Diagnosis, Differential
Graves' ophthalmopathy
Young Adult
Age Distribution
visual axis opacification
Internal medicine
retinitis pigmentosa
Severity of illness
medicine
Humans
unilateral
Sex Distribution
Aged
Retrospective Studies
optical coherence tomography
business.industry
primary posterior capsulotomy
thyroid eye disease
medicine.disease
Surgery
Graves Ophthalmopathy
macular hole
Ophthalmology
Cross-Sectional Studies
lcsh:RE1-994
principal components′
Multifocal electroretinogram
business
Follow-Up Studies
Subjects
Details
- Language :
- English
- ISSN :
- 19983689 and 03014738
- Volume :
- 59
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Indian Journal of Ophthalmology
- Accession number :
- edsair.doi.dedup.....52b7096159710e2b7e1b40906b251eb8