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Blood Pressure Variability during Angiography in Patients with Ischemic Stroke and Intracranial Artery Stenosis

Authors :
David Z. Wang
Jingjing Su
Rong Zhao
Jian-Ren Liu
Yi-Sheng Liu
Ge-Fei Li
Yuan Qiao
Hui Pan
Yi-Min Zhu
Xue-Mei Tang
Shuo Wang
Tian-Yu Hou
Liang Shu
Qian Yao
Jie Fang
Ying Zhao
Yi-Lan Wu
Mei-Ting Zhuang
Guo-Hong Cui
Yan-Hui Shi
Feng-Di Liu
Li-Na Chen
Qi-Ting Zhang
Rui-Jue Huang
Source :
International Journal of Hypertension, International Journal of Hypertension, Vol 2020 (2020)
Publication Year :
2020
Publisher :
Hindawi Limited, 2020.

Abstract

Our aim was to investigate factors predicting blood pressure (BP) variability during diagnostic cerebral angiography and associations between BP variability and clinical outcomes in patients with acute and subacute ischemic stroke and intracranial artery stenosis. 114 patients with ischemic stroke and intracranial artery stenosis (stenosis rate >50%) were recruited. Patients who underwent cerebral angiography within 3 days and 3–14 days of disease onset are referred to be Group A and Group S, respectively. BP variability in Group A was defined as the coefficient of variance (CV) of BP. Univariate and multivariate regression analyses were used to identify predictors of CV of BP and associations between CV of BP and clinical outcomes at discharge. In Group A patients, advanced age was associated with increased CV of SBP and diastolic blood pressure (DBP), and antihypertensive use was associated with lower CV of SBP. Male was associated with lower CV of DBP. In Group S, higher CV of SBP was associated with hypertension and antihypertensive use. Males had lower CV of SBP than females. The calcium channel blocker was associated with lower CV of DBP. Higher scores of the Stroke Scale at admission were significantly associated with poor clinical outcomes for both groups, while BP variability was not. Factors associated with BP variability are significantly different between stroke patients undergoing angiography within 3 days vs. 3–14 days after disease onset. BP variability is not significantly associated with clinical outcomes at discharge.

Details

ISSN :
20900392 and 20900384
Volume :
2020
Database :
OpenAIRE
Journal :
International Journal of Hypertension
Accession number :
edsair.doi.dedup.....52ac3d451c0a014a16792358528074f9