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First clinical experiences with hormone-therapy of pachydermia laryngis
- Source :
- Archives of Oto-Rhino-Laryngology. 221:221-225
- Publication Year :
- 1978
- Publisher :
- Springer Science and Business Media LLC, 1978.
-
Abstract
- First clinical experiences with the anti-androgenic drug cyproterone-acetate in treatment of pachydermia laryngis are reported in eleven male and female patients. This endocrine therapy led to complete healing in four and to marked improvement in six patients. One did not respond. Evaluation of the endocrine state of these patients showed imbalance in the androgen/estrogen equilibrium. As the larynx constitutes a secondary sex characteristic and an endocrine target organ, the significance of endocrine factors for pathogenesis and therapy of epithelial changes on the vocal cords is discussed.
- Subjects :
- Male
Larynx
Hirsutism
medicine.medical_specialty
medicine.drug_class
medicine.medical_treatment
Physiology
Laryngeal Diseases
chemistry.chemical_compound
medicine
Humans
Endocrine system
Cyproterone
Laryngeal Neoplasms
Gynecology
biology
business.industry
Cyproterone acetate
Androgen Antagonists
General Medicine
Laryngeal Edema
Middle Aged
Androgen
biology.organism_classification
medicine.anatomical_structure
Otorhinolaryngology
chemistry
Pachydermia
Estrogen
Female
Neurosurgery
Hormone therapy
Leukoplakia, Oral
business
Subjects
Details
- ISSN :
- 14344726 and 03029530
- Volume :
- 221
- Database :
- OpenAIRE
- Journal :
- Archives of Oto-Rhino-Laryngology
- Accession number :
- edsair.doi.dedup.....52abe3d75ede20f88769587ca59237a2