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Factors associated with relative muscle strength in patients with type 2 diabetes mellitus
- Source :
- Archives of gerontology and geriatrics. 95
- Publication Year :
- 2020
-
Abstract
- Objectives Some patients with type 2 diabetes mellitus (T2DM) experience decreased mobility associated with lower relative muscle strength (normalized with muscle mass). This study aimed to identify factors predicting relative muscle strength of patients with T2DM assessed at regular clinical visits. Methods A total of 144 T2DM patients underwent fasting blood drawing (determining white blood cell count [WBC], diabetic kidney disease [DKD], and glycated hemoglobin [HbA1c]) and the assessment of body composition, diabetic peripheral neuropathy (DPN), activity level, and muscle strength (grip, knee extensor, and ankle plantar flexor strength). One-way ANOVA and multiple regression models were used to identify factors associated with the relative muscle strength. Results Our data showed that age, diabetes duration, fat percentage, WBC, DPN, and DKD were negatively associated with the relative muscle strength. Specifically, a greater WBC was associated with lower relative muscle strength of both distal and proximal muscle groups of extremities after the adjustment of other associated factors. DPN was associated with lower relative strength of the distal muscle groups of extremities. Conclusions WBC may be used as a marker of inflammation, and greater count, even within the normal range, is negatively associated with the relative muscle strength in patients with T2DM.
- Subjects :
- Aging
medicine.medical_specialty
Health (social science)
Urology
Relative strength
Distal Muscle
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Diabetic Neuropathies
White blood cell
medicine
Humans
Knee
030212 general & internal medicine
Muscle Strength
Glycated Hemoglobin
030214 geriatrics
business.industry
Type 2 Diabetes Mellitus
medicine.disease
Peripheral neuropathy
medicine.anatomical_structure
chemistry
Diabetes Mellitus, Type 2
Proximal Muscle
Glycated hemoglobin
Geriatrics and Gerontology
business
Gerontology
Blood drawing
Subjects
Details
- ISSN :
- 18726976
- Volume :
- 95
- Database :
- OpenAIRE
- Journal :
- Archives of gerontology and geriatrics
- Accession number :
- edsair.doi.dedup.....52a84bba46b27988c54de31693bd0ab6