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Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1
- Source :
- Leukemia. 31:1625-1629
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1
- Subjects :
- 0301 basic medicine
Cancer Research
medicine.medical_specialty
Chronic lymphocytic leukemia
Receptors, Cytoplasmic and Nuclear
Apoptosis
Drug resistance
Karyopherins
Biology
Fusion gene
03 medical and health sciences
0302 clinical medicine
Internal medicine
medicine
Humans
Gene
Regulation of gene expression
Hematology
Gene Expression Regulation, Leukemic
Triazoles
medicine.disease
Leukemia, Lymphocytic, Chronic, B-Cell
Haematopoiesis
Leukemia
Hydrazines
030104 developmental biology
Oncology
Drug Resistance, Neoplasm
Chromosomes, Human, Pair 2
030220 oncology & carcinogenesis
Cancer research
Subjects
Details
- ISSN :
- 14765551 and 08876924
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Leukemia
- Accession number :
- edsair.doi.dedup.....52953795c1d61f45d930265677e63ea9