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Syntheses with isotopically labelled carbon. Methyl iodide, formaldehyde and cyanide
- Source :
- The International Journal of Applied Radiation and Isotopes. 35:323-335
- Publication Year :
- 1984
- Publisher :
- Elsevier BV, 1984.
-
Abstract
- Many of the uniquely labelled synthetic precursors currently employed in the design of sophisticated radiolabelled compounds have their origins in the field of hot atom chemistry. Particularly, the development during the past few years of automated, on-line synthetic procedures which combine the nuclear reaction, hot atom and classical chemistry, and rapid purification methods has allowed the incorporation of useful radionuclides into suitable compounds of chemical and biochemical interest. The application of isotopically labelled methyl iodide, formaldehyde, and cyanide anion as synthetic intermidiates in research involving human physiology and nuclear medicine, as well as their contributions to other scientific methodology, is reviewed.
- Subjects :
- Magnetic Resonance Spectroscopy
Cyanide
Carboxylic Acids
Formaldehyde
chemistry.chemical_element
chemistry.chemical_compound
Nitriles
Humans
Organic chemistry
Radiology, Nuclear Medicine and imaging
Carbon Radioisotopes
Amines
Amino Acids
Hydrocarbons, Iodinated
Purification methods
Cyanide anion
Cyanides
Radiation
Hot atom
Proteins
Human physiology
Enzymes
Nuclear Energy and Engineering
chemistry
Isotope Labeling
Viruses
Indicators and Reagents
Carbon
Methyl iodide
Subjects
Details
- ISSN :
- 0020708X
- Volume :
- 35
- Database :
- OpenAIRE
- Journal :
- The International Journal of Applied Radiation and Isotopes
- Accession number :
- edsair.doi.dedup.....528a2c671f6efd70de843244381de9fa