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Indications for Autologous and Allogeneic Hematopoietic Cell Transplantation: Guidelines from the American Society for Blood and Marrow Transplantation
- Source :
- Biology of Blood and Marrow Transplantation. (11):1863-1869
- Publisher :
- American Society for Blood and Marrow Transplantation. Published by Elsevier Inc.
-
Abstract
- Approximately 20,000 hematopoietic cell transplantation (HCT) procedures are performed in the United States annually. With advances in transplantation technology and supportive care practices, HCT has become safer, and patient survival continues to improve over time. Indications for HCT continue to evolve as research refines the role for HCT in established indications and identifies emerging indications where HCT may be beneficial. The American Society for Blood and Marrow Transplantation (ASBMT) established a multiple-stakeholder task force consisting of transplant experts, payer representatives, and a patient advocate to provide guidance on "routine" indications for HCT. This white paper presents the recommendations from the task force. Indications for HCT were categorized as follows: (1) Standard of care, where indication for HCT is well defined and supported by evidence; (2) Standard of care, clinical evidence available, where large clinical trials and observational studies are not available but HCT has been shown to be effective therapy; (3) Standard of care, rare indication, for rare diseases where HCT has demonstrated effectiveness but large clinical trials and observational studies are not feasible; (4) Developmental, for diseases where preclinical and/or early phase clinical studies show HCT to be a promising treatment option; and (5) Not generally recommended, where available evidence does not support the routine use of HCT. The ASBMT will periodically review these guidelines and will update them as new evidence becomes available.
- Subjects :
- Adult
medicine.medical_specialty
Autologous transplantation
Allogeneic transplantation
medicine.medical_treatment
Hematopoietic stem cell transplantation
Transplantation, Autologous
Article
Rare Diseases
Clinical trials
immune system diseases
hemic and lymphatic diseases
medicine
Humans
Transplantation, Homologous
Standard of care
Intensive care medicine
Child
Societies, Medical
Bone Marrow Transplantation
Routine care
Clinical Trials as Topic
Transplantation
Hematopoietic cell transplantation
Hematopoietic cell
Marrow transplantation
business.industry
Age Factors
Hematopoietic Stem Cell Transplantation
Hematology
United States
Surgery
Clinical trial
surgical procedures, operative
Hematologic Neoplasms
Observational study
Indications
business
Subjects
Details
- Language :
- English
- ISSN :
- 10838791
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Biology of Blood and Marrow Transplantation
- Accession number :
- edsair.doi.dedup.....52807cb2064d10b546e3dd9b809d424c
- Full Text :
- https://doi.org/10.1016/j.bbmt.2015.07.032