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Sustainable extraction techniques for obtaining antioxidant and anti-inflammatory compounds from the Lamiaceae and Asteraceae species
- Source :
- Digital.CSIC. Repositorio Institucional del CSIC, instname, Foods, Volume 10, Issue 9, Foods, Vol 10, Iss 2067, p 2067 (2021)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2021.
-
Abstract
- This article belongs to the Special Issue Phenolic Compounds in Herbs: Characterization, Antioxidant Properties and Health Benefits.<br />Melissa officinalis L. and Origanum majorana L., within Lamiaceae family, and Calendula officinalis L. and Achillea millefolium L., within the Asteraceae, have been considered a good source of bioactive ingredients with health benefits. In this study, the supercritical fluid extraction (SFE) using pure CO2, and the ultrasound assisted extraction (UAE) were proposed as green techniques to obtain plant-based extracts with potential antioxidant and anti-inflammatory activities. Higher values of total phenolic content and antioxidant activity were achieved in UAE ethanol:water (50:50, v/v) extracts. Meanwhile, UAE pure ethanol extracts showed greater anti-inflammatory activity. RP-HPLC-PAD-ESI-QTOF-MS/MS analysis showed a vast number of phenolic compounds in the extracts, including unreported ones. O. majorana ethanol:water extract presented the highest content of phenolics and antioxidant activity; among its composition, both rosmarinic acid and luteolin glucoside derivatives were abundant. The pure ethanol extract of A. millefolium resulted in an important content of caffeoylquinic acid derivatives, luteolin-7-O-glucoside and flavonoid aglycones, which could be related to the remarkable inhibition of TNF-α, IL-1β and IL-6 cytokines. Besides, borneol and camphor, found in the volatile fraction of A. millefolium, could contributed to this latter activity. Thus, this study points out that O. majorana and A. millefolium are considered a promising source of bioactive ingredients with potential use in health promotion.<br />Authors thanks to the Spanish Government (Project: PID2019-110183RB-C22/AEI/10.13039/501100011033) and Comunidad Autónoma de Madrid (ALIBIRD2020-CM (S2018/BAA-4343)) for financial support.
- Subjects :
- Health (social science)
antioxidant activity
Achillea millefolium
TP1-1185
Plant Science
complex mixtures
Health Professions (miscellaneous)
Microbiology
Article
chemistry.chemical_compound
Camphor
sustainable extraction
Anti-inflammatory activity
Phenolic composition
Antioxidant activity
anti-inflammatory activity
Origanum majorana
biology
Traditional medicine
Chemical technology
Rosmarinic acid
Origanum
biology.organism_classification
Caffeoylquinic acid
chemistry
Calendula officinalis
Lamiaceae
Sustainable extraction
Melissa officinalis
Food Science
phenolic composition
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- Digital.CSIC. Repositorio Institucional del CSIC, instname, Foods, Volume 10, Issue 9, Foods, Vol 10, Iss 2067, p 2067 (2021)
- Accession number :
- edsair.doi.dedup.....5248417e52b17c1afd4455062ac4b03a