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Spontaneous Regression of Hepatic Adenoma in a Patient with Glycogen Storage Disease Type I after Hemodialysis: Ultrasonographic and CT Findings
- Source :
- Internal Medicine. 40:891-895
- Publication Year :
- 2001
- Publisher :
- Japanese Society of Internal Medicine, 2001.
-
Abstract
- A 23-year-old woman was admitted to our hospital with recurrent gouty arthritis. Laboratory findings showed hypoglycemia, lactic acidosis, hyperlipidemia, and hyperuricemia, with normal values of serum alfa-fetoprotein (AFP) and protein induced by vitamin K absence (PIVKA-II). A diagnosis of glycogen storage disease type I (GSD-type I) was made on the basis of the laboratory data, liver biopsy findings, and partially deficient thrombocyte glucose-6-phosphatase (G-6-Pase) activity. Ultrasonography and computed tomography revealed multiple focal hepatic masses. Biopsied specimens of the lesion demonstrated a hepatic adenoma, which changed in appearance in the relatively short period between echography and computed tomography. This interesting phenomenon may highlight the importance for careful follow-up of hepatic adenomas, because of the potential of rupture, hemorrhage, or malignant transformation. During follow-up, the present patient received hemodialysis due to renal failure, and the adenoma regressed spontaneously after 8 years. Included are diagnostic images, demonstrating the association of hepatic adenoma and GSD-type I.
- Subjects :
- Adult
medicine.medical_specialty
Pathology
Adenoma
Biopsy
medicine.medical_treatment
Glycogen Storage Disease Type I
Hypoglycemia
Gastroenterology
Adenoma, Liver Cell
Renal Dialysis
Internal medicine
Internal Medicine
medicine
Humans
Renal Insufficiency
Hyperuricemia
Ultrasonography
Glycogen storage disease type I
medicine.diagnostic_test
business.industry
Liver Neoplasms
General Medicine
medicine.disease
Liver
Neoplasm Regression, Spontaneous
Lactic acidosis
Liver biopsy
Female
Hemodialysis
Tomography, X-Ray Computed
business
Subjects
Details
- ISSN :
- 13497235 and 09182918
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Internal Medicine
- Accession number :
- edsair.doi.dedup.....5207e4121a8c0b2bff5029511960779a