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The Suicidal Risks and Treatments, Seek Medications from Multi-disciplinary

Authors :
Ting-Ren Lu
Da-Yong Lu
Jin-Yu Che
Peng-Peng Zhu
Source :
Central Nervous System Agents in Medicinal Chemistry. 16:231-239
Publication Year :
2016
Publisher :
Bentham Science Publishers Ltd., 2016.

Abstract

Suicide events and episodes are serious human psychiatric disorders affected by a great number of different environmental/economic factors, early trauma/abuse, human bad living habits, human genomic properties and drug intervention decisions. In order to improve antidepressant therapeutics in clinics, the relationships between efficacy and toxicities of antidepressants have to be considered fundamentally. Since the occurrences and risks of suicidal events or episodes come from interplay between insiders (chemical/genomic/bioinformatics factors) and outsiders (economic/social/ previous trauma conditions and so on), new perspectives and scientific studies must be implemented for revealing these interrelated factors step-by-step and updating therapeutics in human beings. New paradigms and clinical strategies -joint-expert groups and clinical practices (a psychiatrist with other field specialists) should be established for individual patients in future. Thus can some improvements in clinical trials be achieved in a long run?

Details

ISSN :
18715249
Volume :
16
Database :
OpenAIRE
Journal :
Central Nervous System Agents in Medicinal Chemistry
Accession number :
edsair.doi.dedup.....51d7ae06eec7fbac92f06117a0a42038