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Postmortem Serum Amylase and Lipase Analysis in the Diagnosis of Acute Pancreatitis
- Source :
- Academic Forensic Pathology. 8:311-323
- Publication Year :
- 2018
- Publisher :
- SAGE Publications, 2018.
-
Abstract
- The diagnosis of acute pancreatitis, which can occur due to natural and nonnatural causes, is usually made at autopsy based on gross and microscopic examination. However, some pathologists choose to measure serum amylase and lipase levels in postmortem blood samples, which may provide corroborating evidence of acute pancreatitis when evaluated in the context of the autopsy findings. A small series of autopsy cases of deaths related to acute pancreatitis with corresponding postmortem serum amylase and lipase levels and a review of the literature are used to highlight the potential benefits and interpretation issues of postmortem serum amylase and lipase. In autopsies without decomposition, elevated postmortem serum amylase (greater than 1000 U/L) and lipase can provide supportive evidence of acute pancreatitis as a cause of death. However, relying on postmortem serum amylase and lipase alone to diagnose acute pancreatitis is insufficient and unreliable. Rather, one must have the gross and histologic evidence of acute pancreatitis. Acad Forensic Pathol. 2018 8(2): 311-323
- Subjects :
- 0301 basic medicine
Forensic pathology
medicine.medical_specialty
biology
business.industry
Autopsy
Serum amylase
medicine.disease
Gastroenterology
Pathology and Forensic Medicine
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
030220 oncology & carcinogenesis
Internal medicine
biology.protein
medicine
Acute pancreatitis
Invited Reviews
Lipase
business
Subjects
Details
- ISSN :
- 19253621
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Academic Forensic Pathology
- Accession number :
- edsair.doi.dedup.....5180e317e149a4b9e7ed28d5e0cb992a