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Signet-ring cell carcinoma of the prostate mimicking primary gastric carcinoma
- Source :
- Journal of clinical pathology. 45(5)
- Publication Year :
- 1992
-
Abstract
- A post mortem examination of a 70 year old man, who died three years after a poorly differentiated adenocarcinoma of prostate had been diagnosed, showed widespread signet-ring cell carcinoma, with an associated linitis plastica. The signet-ring cells stained positively with prostatic specific antigen and with prostatic specific acid phosphatase, but failed to react with mucopolysaccharide staining. The electron microscopic appearance of the signet-ring cell tumour was due to the presence of large cytoplasmic vacuoles. This case emphasises the possibility that cases of metastatic signet-ring cell carcinoma may be prostatic in origin. This can be confirmed by specific immunohistochemical studies.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Linitis plastica
Cell
Biology
Pathology and Forensic Medicine
Diagnosis, Differential
Prostate
Stomach Neoplasms
Signet ring cell carcinoma
medicine
Humans
Aged
Prostatic Neoplasms
General Medicine
medicine.disease
Adenocarcinoma, Mucinous
Immunohistochemistry
digestive system diseases
Staining
Microscopy, Electron
medicine.anatomical_structure
Adenocarcinoma
Differential diagnosis
Research Article
Subjects
Details
- ISSN :
- 00219746
- Volume :
- 45
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of clinical pathology
- Accession number :
- edsair.doi.dedup.....51527eeb06b1dd09bc954d1461260e0d