Polymeric diet alone versus corticosteroids in the treatment of active pediatric Crohn’s disease

Introduction: Nutritional therapy has been reported to have an almost equivalent efficacy to that of corticosteroids in achieving clinical remission in active Crohn’s disease (CD). However, the effects of both treatments on intestinal mucosal inflammation rarely are reported. In a randomized controlled trial in children with active CD, the authors compared the efficacy of nutritional therapy alone with that of corticosteroids on clinical variables and intestinal mucosal healing.