Evaluation of the hemogram in healthy canines under cisplatin therapy

Made available in DSpace on 2022-04-29T08:44:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-01-01 Objective: To evaluate the average values of the hemogram test in healthy dogs during chemotherapy with cisplatin. Materials and methods: The hemogram parameters of eight healthy canines, which underwent therapy with cisplatin, were evaluated. These canines were divided into two groups. The dogs in the first group were given cisplatin (70mg/m2, i.v.) and to prevent kidney poisoning they were given physiological serum at 0.9% (25mL/kg/h, i.v.). The dogs in group two were not given cisplatin. Results: The hemogram of the dogs in the first group did not show any significant difference (p>0.05) as compared to the dogs in group 2. Conclusion:. The data obtained indicate the protocol used with cisplatine does not significantly alter the average values of the hemogram test and the number of chemotherapy sessions increases the risk of diminishing the values of the hemogram test. Universidad de Nariño Facultad de Ciencias Pecuarias Departamento de Sanidad Animal, Torobajo, Pasto, Nariño Universidad Estatal Paulista Facultad de Medicina Veterinaria y Zootecnia Servicio de Oncología Veterinaria, Jaboticabal, Estado de São Paulo