Sociodemographic Factors and Clinical Profile of Covid-19 Patients Admitted in a Tertiary Care Centre of Central Rajasthan, India

BACKGROUND Covid-2019, caused by severe acute respiratory syndrome-coronavirus-2 (SARS CoV2), is an ongoing pandemic that emerged from China in November 2019. It has affected millions of people worldwide causing significant morbidity and mortality. We wanted to analyse the clinical and demographic profile of Covid-19 patients admitted in a tertiary-care-centre in the central part of Rajasthan, compare their characteristics with other studies published from parts of NorthernIndia and identify factors associated with delayed recovery and mortality. METHODS This was a retrospective observational analysis of the clinical features, and epidemiological profile of Covid-19 positive patients admitted at a tertiary-carecentre in the Central part of Rajasthan. RESULTS A total of 422 patients was enrolled in the study. The male: female ratio was 1.34 with a mean age of 34.1 years. Almost 195 (46.2 %) patients were in the age group of 20 - 40 years. Respiratory diseases were the most common co-morbidity seen in 36 patients (8.53 %), diabetes-mellitus in 28 patients (6.63 %), hypertension in 22 patients (5.2 %). Fever was the commonest presenting symptom (N = 98, 77.17 %), followed by cough (N = 85, 66.93 %), and breathlessness (N = 51, 45.67 %). Factors significantly associated with mortality were age group of 60 - 80 year (P < 0.001), presence of co-morbidities (P < 0.001) and history of smoking & alcohol consumption (P < 0.001). Among co-morbidities diabetes-mellitus, hypertension, chronic-respiratory-diseases & chronic-kidneydiseases had significant impact on mortality. Absence of co-morbidity, lack of addiction and symptoms at the time of presentation were associated with an earlier conversion of reverse transcription polymerase chain reaction (RT-PCR) report. CONCLUSIONS Clinical spectrum of COVID 19 varies widely. Presence of comorbidities, addiction, radiological features has a drastic impact on mortality and duration of infectivity. KEYWORDS SARS CoV-2, Covid-19, RT PCR, Coronavirus