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lncRNA NORAD is consistently detected in breastmilk exosomes and its expression is downregulated in mothers of preterm infants
- Source :
- International Journal of Molecular Medicine
- Publication Year :
- 2021
- Publisher :
- D.A. Spandidos, 2021.
-
Abstract
- Breast milk is the ideal food for infants and undoubtedly has immediate and long‑term benefits. Breast milk contains extracellular vesicles (EVs) i.e., exosomes secreted by maternal breast cells. Exosomes carry genetic material, such as long non‑coding RNAs (lncRNAs), which possibly participate in cell‑to‑cell communications, as they are known to regulate critical gene pathways. The aim of the present study was to screen human breastmilk exosomes for their lncRNA cargo and to examine exosomal lncRNA levels associated with milk obtained from mothers that gave birth at term or prematurely (
- Subjects :
- Adult
Breastfeeding
Down-Regulation
Mothers
breastmilk
exosomes
Breast milk
Biology
Andrology
long non-coding RNAs
Genetics
medicine
Humans
Gene
non-coding RNA activated at DNA damage
Oncogene
Milk, Human
Infant, Newborn
Cancer
preterm birth
General Medicine
Articles
medicine.disease
Molecular medicine
Microvesicles
Breast Feeding
Gene Expression Regulation
Gestation
Female
RNA, Long Noncoding
Infant, Premature
Subjects
Details
- Language :
- English
- ISSN :
- 1791244X and 11073756
- Volume :
- 48
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- International Journal of Molecular Medicine
- Accession number :
- edsair.doi.dedup.....50b82d1703d85ef0350670e716daaef0