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Pulmonary vascular resistance versus pulmonary artery pressure for predicting right ventricular remodeling and functional tricuspid regurgitation
- Source :
- Echocardiography (Mount Kisco, N.Y.). 35(11)
- Publication Year :
- 2018
-
Abstract
- BACKGROUND Pulmonary hypertension (PH) is a common cause of right ventricular (RV) remodeling and functional tricuspid regurgitation (FTR), but incremental pulmonary artery systolic pressure (PASP) does not always correlate with anatomic and functional RV changes. This study aimed to evaluate a noninvasive measure of pulmonary vascular resistance (PVR) for predicting RV dilatation, RV dysfunction, and severity of FTR. METHODS We prospectively analyzed consecutive stable patients with PASP ≥ 35 mm Hg or any degree of RV dilatation or dysfunction secondary to PH. Noninvasive PVR was calculated based on FTR peak velocity and flow in RV outflow tract. RESULTS We included 251 patients, aged 72.1 ± 11.4 years, 53% women, 74.9% with type 2 pulmonary hypertension. The mean PASP was 48.3 ± 12.2 mm Hg. Both PASP and PVR significantly correlated with FTR, RV dilatation, and RV systolic dysfunction. After dichotomizing FTR and RV dilatation and systolic dysfunction as nonsignificant vs significant, FTR and RV dilatation were similarly predicted by PASP and PVR, but RV dysfunction was better predicted by PVR (AUC = 0.78 [0.72-0.84] vs 0.66 [0.60-0.73] for PASP, P
- Subjects :
- Male
medicine.medical_specialty
Heart Ventricles
030204 cardiovascular system & hematology
Doppler echocardiography
Pulmonary Artery
Inferior vena cava
Severity of Illness Index
03 medical and health sciences
0302 clinical medicine
Functional tricuspid regurgitation
medicine.artery
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Arterial Pressure
Prospective Studies
Ventricular remodeling
Aged
medicine.diagnostic_test
Ventricular Remodeling
business.industry
medicine.disease
Pulmonary hypertension
eye diseases
Tricuspid Valve Insufficiency
Blood pressure
medicine.anatomical_structure
030228 respiratory system
medicine.vein
Echocardiography
Pulmonary artery
Cardiology
Vascular resistance
Female
Vascular Resistance
sense organs
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15408175
- Volume :
- 35
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Echocardiography (Mount Kisco, N.Y.)
- Accession number :
- edsair.doi.dedup.....5089ba5c9dfbeae2f67c09e4f74bf5af