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Discriminating Multisystem Inflammatory Syndrome in Children Requiring Treatment from Common Febrile Conditions in Outpatient Settings
- Source :
- The Journal of Pediatrics
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- OBJECTIVES: To examine whether patients with multisystem inflammatory syndrome in children (MIS-C) demonstrated well-defined clinical features distinct from other febrile outpatients, given the difficulties of seeing acute care visits during the severe acute respiratory syndrome coronavirus 2 pandemic and the risks associated with both over- and underdiagnosis of MIS-C. STUDY DESIGN: This case-controlled study compared patients diagnosed with and treated for MIS-C at a large urban children's hospital with patients evaluated for fever at outpatient acute care visits during the peak period of MIS-C. Symptomatology and available objective data were extracted. Comparisons were performed using t tests with corrections for multiple comparisons, and multivariable logistic regression to obtain ORs. RESULTS: We identified 44 patients with MIS-C between April 16 and June 10, 2020. During the same period, 181 pediatric patients were evaluated for febrile illnesses in participating outpatient clinics. Patients with MIS-C reported greater median maximum reported temperature height (40°C vs 38.9, P
- Subjects :
- Male
Multisystem Inflammatory Syndrome in Children, (MIS-C)
medicine.medical_specialty
Abdominal pain
Adolescent
Fever
Objective data
medicine.disease_cause
Logistic regression
Multisystem Inflammatory Syndrome in Children
Intravenous immunoglobulin, (IVIG)
Diagnosis, Differential
03 medical and health sciences
0302 clinical medicine
N-Terminal Brain Natriuretic Peptide, (ntBNP)
030225 pediatrics
Internal medicine
Acute care
Ambulatory Care
medicine
Humans
Outpatient clinic
Pediatrics, Perinatology, and Child Health
030212 general & internal medicine
Child
Emergency Department, (ED)
Retrospective Studies
Neck pain
Kawasaki disease
SARS-CoV-2
business.industry
Age Factors
COVID-19
Original Articles
Rash
Systemic Inflammatory Response Syndrome
Child, Preschool
Pediatrics, Perinatology and Child Health
Female
Symptom Assessment
myocarditis
Irritation
medicine.symptom
business
Subjects
Details
- ISSN :
- 00223476
- Volume :
- 229
- Database :
- OpenAIRE
- Journal :
- The Journal of Pediatrics
- Accession number :
- edsair.doi.dedup.....5072671e43eac8e81b7c5cbe26dc8bb1