Stroke in paediatric pneumococcal meningitis: a cross-sectional population-based study

Before routine infant pneumococcal immunisation and improved access to neuroimaging, around 25% of children with pneumococcal meningitis (PM) suffered ischaemic stroke (IS).1 ,2 In a population-based retrospective audit (UHS ZAUD2053), we investigated the postimmunisation prevalence of stroke/cerebrovascular disease (CVD), and compared features of children with and without IS/CVD. We included all cases of PM in children 5 white cells in the CSF and/or signs of meningism and/or focal neurology and/or meningeal enhancement on CT with contrast. Stroke and/or CVD were identified on CT …