Back to Search
Start Over
Cost-effectiveness of eradication of Helicobacter pylori in gastric cancer survivors after endoscopic resection of early gastric cancer
- Source :
- Helicobacter. 14(6)
- Publication Year :
- 2009
-
Abstract
- Background: Clinical effectiveness of Helicobacter pylori eradication in gastric cancer survivors after endoscopic resection of early gastric cancer (EGC) was recently established in a randomized controlled trial. We aimed to establish long-term cost-effectiveness in gastric cancer survivors after endoscopic resection of EGC. Materials and Methods: A Markov model was constructed to compare the costs and outcomes of the two intervention strategies: (1) eradicate H. pylori after complete resection of EGC by endoscopy (2) do not eradicate. Estimates for variables in the model were obtained by extensive review of published reports. Analyses were made from the Korean public healthcare provider’s perspective. Results: Base-case analysis indicated H. pylori eradication costs less (US$ 29,780 vs. US$ 30,594) than no eradication, and save more lives (mean life expectancy from eradication: 13.60 years vs. 13.55 years). One-way and three-way sensitivity analyses showed the robustness of the cost-effectiveness results. Conclusion: In this selective population with very high risk of developing gastric cancer, H. pylori eradication should be considered for reimbursement with priority to prevent subsequent cancer and also reduce health care cost.
- Subjects :
- Male
medicine.medical_specialty
Cost effectiveness
Cost-Benefit Analysis
Population
macromolecular substances
Gastroenterology
law.invention
Helicobacter Infections
Randomized controlled trial
law
Stomach Neoplasms
Internal medicine
medicine
Humans
Survivors
education
Stomach cancer
Reimbursement
Early Detection of Cancer
Aged
Aged, 80 and over
education.field_of_study
biology
Helicobacter pylori
business.industry
Cancer
Endoscopy
General Medicine
Health Care Costs
Middle Aged
biology.organism_classification
medicine.disease
Early Gastric Cancer
Infectious Diseases
Treatment Outcome
Female
business
Subjects
Details
- ISSN :
- 15235378
- Volume :
- 14
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Helicobacter
- Accession number :
- edsair.doi.dedup.....50460c89b2f70db1eb3853347318c07f