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Distribution of Diplococcus Pneumoniae Types in Acute Otitis Media in Children and Influence of the Types on the Clinical Course in Penicillin V Therapy
- Source :
- Scandinavian Journal of Infectious Diseases. 2:183-190
- Publication Year :
- 1970
- Publisher :
- Informa UK Limited, 1970.
-
Abstract
- Pneumococci isolated from the ear exudate in 245 children under 10 years of age afflicted with acute otitis media were typed. Types 3, 6, 14, 18, 19 and 23 were found in 80% of the cases. In the remaining cases, 15 other types were found. Five strains were not typable with the antisera used. Types 14 and 23 were found twice as often in the age group 0-3 years as in the higher age groups, whereas the opposite was true for type 3. The relapse frequency was highest after types 14 and 19 infections. The frequency of residual secretory otitis was highest after type 14 infections. Types 19 and 23 were never found in infections followed by secretory otitis. Patients with type 14 infections, healed or unhealed, showed the same blood group distribution within the ABO and Lewis systems as a normal Swedish population. Penicillin V therapy failed to eliminate the pneumococcal strain from the nasopharynx in 40% of consecutive cases of otitis media. Relapse after penicillin-treated pneumococcal otitis is to be regarded as a new complication of the primary infection and not as a reinfection from the environment.
- Subjects :
- Microbiology (medical)
medicine.medical_specialty
General Immunology and Microbiology
business.industry
Acute otitis media
Clinical course
General Medicine
Penicillin
Infectious Diseases
Otitis
Otorhinolaryngology
Internal medicine
ABO blood group system
Immunology
Diplococcus pneumoniae
Medicine
Distribution (pharmacology)
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 16511980 and 00365548
- Volume :
- 2
- Database :
- OpenAIRE
- Journal :
- Scandinavian Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....50319b2e516494dd2a9bab46d70ed8b0