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Metabolically-defined body size phenotypes and risk of endometrial cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)
- Source :
- Kliemann, N, Ammar, R O, Biessy, C, Gicquiau, A, Katzke, V, Kaaks, R, Tjonneland, A, Olsen, A, Sanchez, M-J, Crous-Bou, M, Pasanisi, F, Tin, S T, Perez-Cornago, A, Aune, D, Christakoudi, S, Heath, A K, Colorado-Yohar, S M, Grioni, S, Skeie, G, Sartor, H, Idahl, A, Rylander, C, May, A M, Weiderpass, E, Freisling, H, Playdon, M C, Rinaldi, S, Murphy, N, Huybrechts, I, Dossus, L & Gunter, M J 2022, ' Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer Epidemiology, Biomarkers & Prevention, vol. 31, no. 7, pp. 1359-1367 . https://doi.org/10.1158/1055-9965.EPI-22-0160, Dipòsit Digital de la UB, Universidad de Barcelona, Kliemann, N, Ould Ammar, R, Biessy, C, Gicquiau, A, Katzke, V, Kaaks, R, Tjønneland, A, Olsen, A, Sánchez, M-J, Crous-Bou, M, Pasanisi, F, Tin Tin, S, Perez-Cornago, A, Aune, D, Christakoudi, S, Heath, A K, Colorado-Yohar, S M, Grioni, S, Skeie, G, Sartor, H, Idahl, A, Rylander, C, May, A M, Weiderpass, E, Freisling, H, Playdon, M C, Rinaldi, S, Murphy, N, Huybrechts, I, Dossus, L & Gunter, M J 2022, ' Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer Epidemiology, Biomarkers & Prevention, vol. 31, no. 7, pp. 1359-1367 . https://doi.org/10.1158/1055-9965.EPI-22-0160
- Publication Year :
- 2022
- Publisher :
- American Association for Cancer Research, 2022.
-
Abstract
- Background: Obesity is a risk factor for endometrial cancer but whether metabolic dysfunction is associated with endometrial cancer independent of body size is not known. Methods: The association of metabolically defined body size phenotypes with endometrial cancer risk was investigated in a nested case–control study (817 cases/ 817 controls) within the European Prospective Investigation into Cancer and Nutrition (EPIC). Concentrations of C-peptide were used to define metabolically healthy (MH<br />World Health Organization<br />Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London<br />Danish Cancer Society<br />Ligue nationale contre le cancer<br />Institut Gustave Roussy<br />Mutuelle Generale de l'Education Nationale<br />Institut National de la Sante et de la Recherche Medicale (Inserm)<br />Deutsche Krebshilfe<br />Helmholtz Association<br />German Institute of Human Nutrition PotsdamRehbruecke (DIfE)<br />Federal Ministry of Education & Research (BMBF)<br />Fondazione AIRC per la ricerca sul cancro<br />Compagnia di San Paolo<br />Consiglio Nazionale delle Ricerche (CNR)<br />Dutch Ministry of Public Health, Welfare and Sports (VWS)<br />Netherlands Cancer Registry (NKR)<br />LK Research Funds<br />Dutch Prevention Funds Netherlands Organization for Scientific Research (NWO)<br />World Cancer Research Fund (WCRF-ERC) 232997<br />Netherlands Government<br />Health Research Fund (FIS)-Instituto de Salud Carlos III (ISCIII)<br />Junta de Andalucia<br />Principality of Asturias<br />Basque Government<br />Regional Government of Murcia<br />Regional Government of Navarra<br />Catalan Institute of OncologyICO (Spain)<br />Swedish Cancer Society Swedish Research Council<br />European Commission<br />County Council of Skane<br />County Council of Vasterbotten (Sweden)<br />Cancer Research UK 14136 C8221/A29017 C19335/A21351<br />UK Research & Innovation (UKRI)<br />Medical Research Council UK (MRC)<br />European Commission 1000143 MR/M012190/1
- Subjects :
- Endometrial Neoplasms/complications
Epidemiology
Trastorns del metabolisme
Risk factors in diseases
C-PEPTIDE
Body Mass Index
MASS INDEX
Endometrial cancer
Risk Factors
Body Size
Humans
Obesity
Prospective Studies
Factores de riesgo en enfermedades
VALIDITY
11 Medical and Health Sciences
Cancer och onkologi
INSULIN-RESISTANCE
OVERWEIGHT
C-Peptide
Public Health, Global Health, Social Medicine and Epidemiology
Endometrial Neoplasms
Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi
ESTROGEN
Phenotype
Disorders of metabolism
Oncology
Càncer d'endometri
Case-Control Studies
Cancer and Oncology
OBESITY
Obesitat
GROWTH
Female
HEALTH
Obesity/complications
ANTHROPOMETRIC FACTORS
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Kliemann, N, Ammar, R O, Biessy, C, Gicquiau, A, Katzke, V, Kaaks, R, Tjonneland, A, Olsen, A, Sanchez, M-J, Crous-Bou, M, Pasanisi, F, Tin, S T, Perez-Cornago, A, Aune, D, Christakoudi, S, Heath, A K, Colorado-Yohar, S M, Grioni, S, Skeie, G, Sartor, H, Idahl, A, Rylander, C, May, A M, Weiderpass, E, Freisling, H, Playdon, M C, Rinaldi, S, Murphy, N, Huybrechts, I, Dossus, L & Gunter, M J 2022, ' Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer Epidemiology, Biomarkers & Prevention, vol. 31, no. 7, pp. 1359-1367 . https://doi.org/10.1158/1055-9965.EPI-22-0160, Dipòsit Digital de la UB, Universidad de Barcelona, Kliemann, N, Ould Ammar, R, Biessy, C, Gicquiau, A, Katzke, V, Kaaks, R, Tjønneland, A, Olsen, A, Sánchez, M-J, Crous-Bou, M, Pasanisi, F, Tin Tin, S, Perez-Cornago, A, Aune, D, Christakoudi, S, Heath, A K, Colorado-Yohar, S M, Grioni, S, Skeie, G, Sartor, H, Idahl, A, Rylander, C, May, A M, Weiderpass, E, Freisling, H, Playdon, M C, Rinaldi, S, Murphy, N, Huybrechts, I, Dossus, L & Gunter, M J 2022, ' Metabolically Defined Body Size Phenotypes and Risk of Endometrial Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', Cancer Epidemiology, Biomarkers & Prevention, vol. 31, no. 7, pp. 1359-1367 . https://doi.org/10.1158/1055-9965.EPI-22-0160
- Accession number :
- edsair.doi.dedup.....502ee8c3a5607483d22eeadb6469a209