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A snapshot of antimicrobial resistance in Mexico. Results from 47 centers from 20 states during a six-month period
- Source :
- PLoS ONE, Vol 14, Iss 3, p e0209865 (2019), PLoS ONE
- Publication Year :
- 2019
- Publisher :
- Public Library of Science (PLoS), 2019.
-
Abstract
- Aim We aimed to assess the resistance rates of antimicrobial-resistant, in bacterial pathogens of epidemiological importance in 47 Mexican centers. Material and methods In this retrospective study, we included a stratified sample of 47 centers, covering 20 Mexican states. Selected isolates considered as potential causatives of disease collected over a 6-month period were included. Laboratories employed their usual methods to perform microbiological studies. The results were deposited into a database and analyzed with the WHONET 5.6 software. Results In this 6-month study, a total of 22,943 strains were included. Regarding Gram-negatives, carbapenem resistance was detected in ≤ 3% in Escherichia coli, 12.5% in Klebsiella sp. and Enterobacter sp., and up to 40% in Pseudomonas aeruginosa; in the latter, the resistance rate for piperacillin-tazobactam (TZP) was as high as 19.1%. In Acinetobacter sp., resistance rates for cefepime, ciprofloxacin, meropenem, and TZP were higher than 50%. Regarding Gram-positives, methicillin resistance in Staphylococcus aureus (MRSA) was as high as 21.4%, and vancomycin (VAN) resistance reached up to 21% in Enterococcus faecium. Acinetobacter sp. presented the highest multidrug resistance (53%) followed by Klebsiella sp. (22.6%) and E. coli (19.4%). Conclusion The multidrug resistance of Acinetobacter sp., Klebsiella sp. and E. coli and the carbapenem resistance in specific groups of enterobacteria deserve special attention in Mexico. Vancomycin-resistant enterococci (VRE) and MRSA are common in our hospitals. Our results present valuable information for the implementation of measures to control drug resistance.
- Subjects :
- Male
0301 basic medicine
Research Facilities
Drug resistance
Pathology and Laboratory Medicine
Geographical locations
Antibiotics
Drug Resistance, Multiple, Bacterial
Klebsiella
Epidemiology
Prevalence
Medicine and Health Sciences
Multidisciplinary
Acinetobacter
Antimicrobials
Drugs
Pseudomonas Aeruginosa
Bacterial Pathogens
Medical Microbiology
Medicine
Female
Pathogens
Research Laboratories
Research Article
medicine.medical_specialty
Science
030106 microbiology
Research and Analysis Methods
Microbiology
03 medical and health sciences
Antibiotic resistance
Microbial Control
Pseudomonas
Environmental health
Gram-Negative Bacteria
Escherichia coli
medicine
Humans
Mexico
Microbial Pathogens
Retrospective Studies
Pharmacology
Bacteria
business.industry
Organisms
Biology and Life Sciences
biochemical phenomena, metabolism, and nutrition
030104 developmental biology
Multicenter study
Antibiotic Resistance
North America
Antimicrobial Resistance
People and places
Gram-Negative Bacterial Infections
business
Software
Government Laboratories
Subjects
Details
- ISSN :
- 19326203
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- PLOS ONE
- Accession number :
- edsair.doi.dedup.....501ebfa2c693d461b95c15fc943bf881