Oral squamous cell carcinoma incidence by subsite among diverse racial and ethnic populations in California

Objective. The aim of this report was to examine the oral cancer incidence by sex, race/ethnicity, and anatomical subsite. Study design. Data from the California Cancer Registry (CCR) were used to calculate the age-adjusted incidence rates of invasive oral squamous cell carcinoma (OSCC) by sex, race/ethnicity, and anatomical subsite among residents in California during 1988 to 2001. Results. Although non-Hispanic (NH) black men have the highest overall incidence rate for OSCC, NH whites and NH blacks have similar incidence patterns by subsite, but the male-to-female (M:F) rate ratio is higher among NH blacks. The OSCC incidence rates for Hispanics are much lower than those for NH whites and NH blacks and similar to those of Asians. The Asian ethnic groups display dramatic variations in terms of the subsite-specific incidence rates and M:F rate ratios. Conclusion. The findings illustrate the heterogeneity and complexity of oral cancer by anatomical location and the importance of cultural habits and behavioral factors in the development of oral cancer. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:470-80)