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Inhibition of hERG Channel Trafficking: An Under-Explored Mechanism for Drug-Induced QT Prolongation
- Source :
- ChemMedChem. 3:1501-1502
- Publication Year :
- 2008
- Publisher :
- Wiley, 2008.
- Subjects :
- ERG1 Potassium Channel
Long QT syndrome
hERG
Pharmacology
Biochemistry
Ion Channels
Inhibitory Concentration 50
Fluoxetine
Drug Discovery
medicine
Humans
Inhibitory concentration 50
General Pharmacology, Toxicology and Pharmaceutics
Ion channel
biology
Mechanism (biology)
business.industry
Organic Chemistry
Drug-induced QT prolongation
medicine.disease
Ether-A-Go-Go Potassium Channels
Long QT Syndrome
Protein Transport
Ketoconazole
biology.protein
Molecular Medicine
business
Subjects
Details
- ISSN :
- 18607187 and 18607179
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- ChemMedChem
- Accession number :
- edsair.doi.dedup.....4fe051730dde4d5add960ef81a8a2e96
- Full Text :
- https://doi.org/10.1002/cmdc.200800170