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ARRIVE has not ARRIVEd: Support for the ARRIVE (Animal Research: Reporting of in vivo Experiments) guidelines does not improve the reporting quality of papers in animal welfare, analgesia or anesthesia
- Source :
- PLoS ONE, PLoS ONE, Vol 13, Iss 5, p e0197882 (2018)
- Publication Year :
- 2018
- Publisher :
- Public Library of Science, 2018.
-
Abstract
- Poor research reporting is a major contributing factor to low study reproducibility, financial and animal waste. The ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines were developed to improve reporting quality and many journals support these guidelines. The influence of this support is unknown. We hypothesized that papers published in journals supporting the ARRIVE guidelines would show improved reporting compared with those in non-supporting journals. In a retrospective, observational cohort study, papers from 5 ARRIVE supporting (SUPP) and 2 non-supporting (nonSUPP) journals, published before (2009) and 5 years after (2015) the ARRIVE guidelines, were selected. Adherence to the ARRIVE checklist of 20 items was independently evaluated by two reviewers and items assessed as fully, partially or not reported. Mean percentages of items reported were compared between journal types and years with an unequal variance t-test. Individual items and sub-items were compared with a chi-square test. From an initial cohort of 956, 236 papers were included: 120 from 2009 (SUPP; n = 52, nonSUPP; n = 68), 116 from 2015 (SUPP; n = 61, nonSUPP; n = 55). The percentage of fully reported items was similar between journal types in 2009 (SUPP: 55.3 ± 11.5% [SD]; nonSUPP: 51.8 ± 9.0%; p = 0.07, 95% CI of mean difference -0.3-7.3%) and 2015 (SUPP: 60.5 ± 11.2%; nonSUPP; 60.2 ± 10.0%; p = 0.89, 95%CI -3.6-4.2%). The small increase in fully reported items between years was similar for both journal types (p = 0.09, 95% CI -0.5-4.3%). No paper fully reported 100% of items on the ARRIVE checklist and measures associated with bias were poorly reported. These results suggest that journal support for the ARRIVE guidelines has not resulted in a meaningful improvement in reporting quality, contributing to ongoing waste in animal research.
- Subjects :
- 0301 basic medicine
Research Report
Economics
lcsh:Medicine
Animal Slaughter
Social Sciences
0302 clinical medicine
Anesthesiology
Medicine and Health Sciences
lcsh:Science
Animal Management
Analgesics
Multidisciplinary
Publications
Drugs
Agriculture
Research Assessment
Checklist
3. Good health
Test (assessment)
Research Design
Cohort
Research Reporting Guidelines
Guideline Adherence
Cohort study
Research Article
Animal Experimentation
medicine.medical_specialty
Clinical Research Design
MEDLINE
Research and Analysis Methods
Animal Welfare
03 medical and health sciences
Animal welfare
medicine
Pain Management
Animals
Humans
Scientific Publishing
Anesthetics
Retrospective Studies
Pharmacology
business.industry
lcsh:R
Biology and Life Sciences
Retrospective cohort study
030104 developmental biology
Family medicine
lcsh:Q
Adverse Events
business
030217 neurology & neurosurgery
Finance
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 13
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....4fd83ee3e61d804332d57ebbf147c269