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Postural disorders in Parkinson’s disease
- Source :
- Neurophysiologie Clinique = Clinical Neurophysiology, Neurophysiologie Clinique = Clinical Neurophysiology, 2008, 38 (6), pp.459-465. ⟨10.1016/j.neucli.2008.07.006⟩, Neurophysiologie Clinique/Clinical Neurophysiology, Neurophysiologie Clinique/Clinical Neurophysiology, Elsevier Masson, 2008, 38 (6), pp.459-465. ⟨10.1016/j.neucli.2008.07.006⟩
- Publication Year :
- 2008
- Publisher :
- Elsevier BV, 2008.
-
Abstract
- Posture is often affected in Parkinson's disease. Postural abnormalities belong to the motor axial involvement. Generally, postural dysfunction induces clinical impairment at the latest stages of the disease, except in late-onset idiopathic Parkinson's disease and in atypical parkinsonian syndromes. Posture may be affected in its orientation component (stooped posture, camptocormia, Pisa syndrome) or in its balance component (loss of postural reflexes). Overall, postural impairment is poorly improved by levodopa, which implies that it is unlikely due to the nigrostriatal dopaminergic denervation. Several methods of investigation have been proposed but are generally not available in clinical practice. Medical treatment and deep brain stimulation (DBS) of the subthalamic nucleus or globus pallidus pars interna are less efficient on axial than on distal motor signs. The pedonculopontine nucleus seems promising as a new target for DBS in combination with the subthalamic nucleus. Physical therapy is, in most cases, the best way to improve postural dysfunction.
- Subjects :
- 030506 rehabilitation
Levodopa
Parkinson's disease
Deep brain stimulation
medicine.medical_treatment
Posture
03 medical and health sciences
Camptocormia
0302 clinical medicine
Physiology (medical)
medicine
Postural Balance
Humans
[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs
ComputingMilieux_MISCELLANEOUS
Balance (ability)
[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior
[SCCO.NEUR]Cognitive science/Neuroscience
[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences
Parkinson Disease
General Medicine
medicine.disease
Biomechanical Phenomena
nervous system diseases
3. Good health
Subthalamic nucleus
Globus pallidus
Neurology
Sensation Disorders
Neurology (clinical)
0305 other medical science
Psychology
Neuroscience
030217 neurology & neurosurgery
medicine.drug
Subjects
Details
- ISSN :
- 09877053
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- Neurophysiologie Clinique/Clinical Neurophysiology
- Accession number :
- edsair.doi.dedup.....4fd0132d54a04e50faeb47d9ac762a70