Sperm DNA integrity: from ‘promising’ to standardization

Human assisted reproduction results have improved dramatically in the last 20 years, with lower complications for the patient as well as for the newborns. This requires a precise clinical diagnosis that will allow us to individualize the best-personalized treatment for each patient or couple. But still today, the basic diagnostic test for the male is a conventional sperm analysis, even though it has been extensively discussed the difficulties that this simple test reveals to discriminate between fertile and infertile individuals.