Supplementary Figures 1 - 5 from ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer

Supplementary Figure 1. UPR genes in DU145 cells. Supplementary Figure 2. ONC201 does not inhibit translocation of AR-GFP to the nucleus upon DHT treatment and does not induce AR degradation. Supplementary Figure 3. ONC201 partly synergizes with docetaxol. Supplementary Figure 4. ONC201 partly synergizes with crizotinib. Supplementary Figure 5. Biweekly measurements of mouse weights after the indicated treatments in different prostate cancer xenograft models.