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The first multi-centre point-prevalence survey in four Japanese university hospitals
- Source :
- Journal of Hospital Infection. 99:325-331
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Summary Background The Japanese government adopted a national action plan on antimicrobial resistance, which aims to reduce drug-resistant pathogens and antimicrobial use. A point-prevalence survey (PPS) is a useful surveillance method to gain information about hospital epidemiology; however, no multi-centre PPS has previously been performed in Japan. Aim To investigate general information about hospital epidemiology, healthcare-associated infections (HCAIs), and antimicrobial use in multiple Japanese university hospitals. Methods In July 2016, a multi-centre PPS was conducted using a standardized protocol at four university hospitals in Japan. Findings A total of 3199 patients were included. Median age and duration of hospital stay were 64 years and 10 days, respectively. A total of 246 (7.7%; 95% confidence interval (CI): 6.8–8.7) patients had 256 active HCAIs, and 933 (29.2%; 95% CI: 27.6–30.8) patients received 1318 antimicrobials. Pneumonia and gastrointestinal system infection were the most common HCAIs (N = 42, 16.4%), and Enterobacteriaceae (N = 49, 30.8%) were the predominant causative organisms. Carbapenems (N = 52, 17.8%), anti-MRSA medications, and cephems with antipseudomonal activity were the most frequently prescribed antimicrobials for HCAIs. As surgical prophylaxis, 46 of 278 antimicrobials (16.5%) were administered orally. Proportions of HCAI and antimicrobial use in each hospital ranged from 4.8% to 9.5% and 19.3%–35.0%, respectively. Conclusion This multi-centre PPS recorded detailed HCAI data and distinct antimicrobial use in Japanese university hospitals. Further surveillance is necessary to reduce HCAIs and formulate feasible plans to achieve the national action plan on antimicrobial resistance.
- Subjects :
- Adult
Male
0301 basic medicine
Microbiology (medical)
Point prevalence survey
medicine.medical_specialty
Adolescent
030106 microbiology
Hospitals, University
Young Adult
03 medical and health sciences
Surgical prophylaxis
0302 clinical medicine
Antibiotic resistance
Enterobacteriaceae
Japan
Surveys and Questionnaires
Internal medicine
Prevalence
medicine
Humans
030212 general & internal medicine
Multi centre
Child
Aged
Aged, 80 and over
Cross Infection
business.industry
Enterobacteriaceae Infections
Infant, Newborn
Infant
General Medicine
Middle Aged
University hospital
Antimicrobial
medicine.disease
Drug Utilization
Confidence interval
Anti-Bacterial Agents
Pneumonia
Infectious Diseases
Child, Preschool
Female
business
Subjects
Details
- ISSN :
- 01956701
- Volume :
- 99
- Database :
- OpenAIRE
- Journal :
- Journal of Hospital Infection
- Accession number :
- edsair.doi.dedup.....4f80aa5408106b6ae0ee53e3f914bdc4
- Full Text :
- https://doi.org/10.1016/j.jhin.2018.03.005