Combined UGT1A1 and UGT1A6 genotypes together with a stressful life event increase breast cancer risk

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany Cor respondence to Dr Christina Justenhoven , Dr Margarete Fischer -Bosch -Institute of Clinical Pharmacology, Auerbachstrasse 112, D -70376 Stuttgart , Germany Tel: + 49 711 81015765; fax + 49 711 859295; e -mail: christina.justenhoven @ikp -stuttgart.de Key words : UGT1A1; UGT1A6: polymorphisms; stressful life event; breast cancer risk To the Editor, B reast cancer is a multifactor disease and causative factor s include genetic variations i. e. mutations and polymorphisms as well as epidemiological risks . BRCA1 and B RCA 2 germline peer-00563447, version 1 - 5 Feb 2011