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The clinical effect of smoking and environmental factors in spontaneous pneumothorax: a case-crossover study in an Inland province
- Source :
- Therapeutic Advances in Respiratory Disease, Therapeutic Advances in Respiratory Disease, Vol 14 (2020)
- Publication Year :
- 2020
- Publisher :
- SAGE Publications, 2020.
-
Abstract
- Background: The factors that trigger spontaneous pneumothorax have not been sufficiently evaluated. The purpose of this study is to analyze the relationship between the development of spontaneous pneumothorax and meteorological parameters, including air pollutants. Methods: This is a retrospective study using the medical records of 379 patients who were admitted for spontaneous pneumothorax (SP) over a period of 4 years. Meteorological and air pollution data were obtained from the National Meteorological Office and the Ministry of Environment. We employed a case-crossover design to evaluate the short-term association between SP and meteorological factors including air pollutants. Conditional logistic regression was used to analyze bi-directional matched data. Results: Increase of relative humidity (RH) and of carbon monoxide (CO) were associated with the risk of pneumothorax, with odds ratio (OR) for RH = 1.18 (1.02–1.36), CO = 1.23 (1.02–1.48). Moreover, as air pressure (AP) decreased, risk of pneumothorax increased, with OR = 1.30 (1.05–1.59) but others did not. In the stratified analysis, the effect of RH was positive in ex-smokers (OR = 3.31) and non-smokers (OR = 1.32), but negative in current smokers (OR = 0.72). The effect of AP was significant in younger patients (OR = 1.33), males (OR = 1.40), and non-smokers (OR = 1.36). CO was related only with non-smokers (OR = 1.35) Conclusion: The triggering factors for spontaneous pneumothorax were relative humidity, carbon monoxide, and air pressure. The effect of the trigger was prominent in patients who were younger (
- Subjects :
- Adult
Male
Pulmonary and Respiratory Medicine
pneumothorax
smokers
030204 cardiovascular system & hematology
03 medical and health sciences
Sex Factors
0302 clinical medicine
Air Pollution
Republic of Korea
medicine
Humans
Pharmacology (medical)
Retrospective Studies
Original Research
lcsh:RC705-779
Air Pressure
Carbon Monoxide
Cross-Over Studies
business.industry
Smoking
Age Factors
humidity
lcsh:Diseases of the respiratory system
Middle Aged
medicine.disease
Crossover study
respiratory tract diseases
030228 respiratory system
Pneumothorax
Anesthesia
Female
business
Subjects
Details
- ISSN :
- 17534666
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- Therapeutic Advances in Respiratory Disease
- Accession number :
- edsair.doi.dedup.....4f39f079bbd5a1f7b8738f46b98e7b30