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Supplementary Table 1 from Population Pharmacokinetics of Busulfan in Children: Increased Evidence for Body Surface Area and Allometric Body Weight Dosing of Busulfan in Children

Authors :
Georg Hempel
Joachim Boos
Mats O. Karlsson
Martin Bergstrand
Mirjam N. Trame
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF file - 75KB, Population model comparison; population parameter estimates Abbreviations: BW body weight, BSA body surface area, CL apparent clearance, V apparent volume of distribution, ka absorption rate constant, F bioavailability, standard errors in brackets, * estimated for a 27.2 kg subject, ** CV% based on simulations (sd(Fi)/mean(Fi)) and in squared parenthesis shows the variance for the logit-transform of F.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....4f16ef0e73cdbdedd3e909774609933a