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A structural magnetic resonance imaging study in therapy-naïve transsexual individuals
- Source :
- Folia Morphologica. 80:442-447
- Publication Year :
- 2021
- Publisher :
- VM Media SP. zo.o VM Group SK, 2021.
-
Abstract
- Background: Transsexuality is explained and defined as a gender-identity disorder, characterised by very strong conviction of belonging to the opposite sex and has been associated with a distinct neuroanatomical pattern. Materials and methods: We performed a structural analysis in search of possible differences in grey matter structures based on magnetic resonance imaging scans of the brains of 26 individuals between 19 and 38 years of age. The participants were divided into two groups of 15 controls and 11 transgender individuals. The segmentation of subcortical grey matter was performed using FIRST model a model-based segmentation/registration tool, from FSL software package. Results: The results showed that the volume of the brain region called nucleus accumbens on the left side was significantly smaller in the group of transgender individuals compared to the control. It was the most important parameter which was shown to make distinction between two examined groups. Conclusions: The results also showed decreased volumes of the left thalamus, right hippocampus and right caudate nucleus.
- Subjects :
- medicine.medical_specialty
Histology
050109 social psychology
Nucleus accumbens
Grey matter
Audiology
Hippocampus
Transgender Persons
Structural magnetic resonance imaging
Therapy naive
0502 economics and business
Transgender
medicine
Humans
0501 psychology and cognitive sciences
Segmentation
Gray Matter
10. No inequality
medicine.diagnostic_test
business.industry
05 social sciences
Brain
Magnetic resonance imaging
Magnetic Resonance Imaging
Transsexual
medicine.anatomical_structure
050211 marketing
Anatomy
business
Subjects
Details
- ISSN :
- 16443284 and 00155659
- Volume :
- 80
- Database :
- OpenAIRE
- Journal :
- Folia Morphologica
- Accession number :
- edsair.doi.dedup.....4ef8578d262e469ba11f1dfce8bcd6d8