Supplementary Figure S1 from The TMPRSS2–ERG Gene Fusion Blocks XRCC4-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP Inhibition

Authors :: Alexandru Almasan
Eric A. Klein
Junran Zhang
Cristina Magi-Galluzzi
Warren D. Heston
Xiahui Xiong
Turkeyah Alswillah
Gaurav S. Choudhary
Payel Chatterjee
Publication Year :: 2023
Publisher :: American Association for Cancer Research (AACR), 2023.
Abstract: TMPRSS2/ERG inhibits Ser2056 DNA-PKcs phosphorylation. Confocal immunostaining for phospho-DNA-PKcs Ser2056 at indicated times following IR in PC3 with or without expression of the TMPRSS2-ERG fusion.

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