Improved Survival in Liver Transplant Recipients Receiving Prolonged-Release Tacrolimus in the European Liver Transplant Registry

Authors :: Paolo Muiesan
Safi Dokmak
Otto Kollmar
Bo-Göran Ericzon
Marek Krawczyk
Giuseppe Tisone
Karim Boudjema
Fausto Zamboni
P. Němec
all contributing centers
R. Hanvesakul
Didier Samuel
Pavel Trunecka
Umberto Baccarani
Vincent Karam
Peter Neuhaus
Philippe Bachellier
O. Rummo
Johann Pratschke
Wolf O. Bechstein
Juergen Klempnauer
Valérie Delvart
Georges Mantion
René Adam
Massimo Rossi
Michele Colledan
Andreas Paul
Adam, R
Karam, V
Delvart, V
Trunecka, P
Samuel, D
Bechstein, W
Nemec, P
Tisone, G
Klempnauer, J
Rossi, M
Rummo, O
Dokmak, S
Krawczyk, M
Pratschke, J
Kollmar, O
Boudjema, K
Colledan, M
Ericzon, B
Mantion, G
Baccarani, U
Neuhaus, P
Paul, A
Bachellier, P
Zamboni, F
Hanvesakul, R
Muiesan, P
Source :: American Journal of Transplantation. 15:1267-1282
Publication Year :: 2015
Publisher :: Elsevier BV, 2015.
Abstract: This study was a retrospective analysis of the European Liver Transplant Registry (ELTR) performed to compare long-term outcomes with prolonged-release tacrolimus versus tacrolimus BD in liver transplantation (January 2008-December 2012). Clinical efficacy measures included univariate and multivariate analyses of risk factors influencing graft and patient survival at 3 years posttransplant. Efficacy measures were repeated using propensity score-matching for baseline demographics. Patients with

Subjects :: Registrie
Graft Rejection
Male
Multivariate analysis
medicine.medical_treatment
Medizin
Improved survival
Kaplan-Meier Estimate
030230 surgery
Liver transplantation
ELTR, long-term outcomes, prolonged-release tacrolimus, acrolimus BD, liver transplantation
Immunosuppressive Agent
0302 clinical medicine
Retrospective Studie
Risk Factors
Immunology and Allergy
Pharmacology (medical)
Registries
Multivariate Analysi
Settore MED/12 - Gastroenterologia
Medicine (all)
Graft Survival
Middle Aged
3. Good health
Europe
Treatment Outcome
surgical procedures, operative
Tacrolimu
Female
030211 gastroenterology & hepatology
Immunotherapy
Immunosuppressive Agents
Human
Adult
medicine.medical_specialty
Aged
Humans
Liver Failure
Liver Transplantation
Multivariate Analysis
Retrospective Studies
Tacrolimus
Transplantation
chemical and pharmacologic phenomena
03 medical and health sciences
Prolonged release
Internal medicine
medicine
In patient
business.industry
Risk Factor
Retrospective cohort study
Liver Transplant Recipients
European Liver Transplant Registry
Surgery
Relative risk
business

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