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Long-Term Exposure to Air Pollutants and Cancer Mortality: A Meta-Analysis of Cohort Studies
- Source :
- International Journal of Environmental Research and Public Health, Vol 15, Iss 11, p 2608 (2018), International Journal of Environmental Research and Public Health, Volume 15, Issue 11
- Publication Year :
- 2018
- Publisher :
- MDPI AG, 2018.
-
Abstract
- The aim of this study was to examine the relationship between main air pollutants and all cancer mortality by performing a meta-analysis. We searched PubMed, EMBASE (a biomedical and pharmacological bibliographic database of published literature produced by Elsevier), and the reference lists of other reviews until April 2018. A random-effects model was employed to analyze the meta-estimates of each pollutant. A total of 30 cohort studies were included in the final analysis. Overall risk estimates of cancer mortality for 10 &micro<br />g/m3 per increase of particulate matter (PM)2.5, PM10, and NO2 were 1.17 (95% confidence interval (CI): 1.11&ndash<br />1.24), 1.09 (95% CI: 1.04&ndash<br />1.14), and 1.06 (95% CI: 1.02&ndash<br />1.10), respectively. With respect to the type of cancer, significant hazardous influences of PM2.5 were noticed for lung cancer mortality and non-lung cancer mortality including liver cancer, colorectal cancer, bladder cancer, and kidney cancer, respectively, while PM10 had harmful effects on mortality from lung cancer, pancreas cancer, and larynx cancer. Our meta-analysis of cohort studies indicates that exposure to the main air pollutants is associated with increased mortality from all cancers.
- Subjects :
- Oncology
Adult
Male
medicine.medical_specialty
Time Factors
Adolescent
Colorectal cancer
Health, Toxicology and Mutagenesis
lcsh:Medicine
010501 environmental sciences
01 natural sciences
Article
Cohort Studies
03 medical and health sciences
Young Adult
0302 clinical medicine
Internal medicine
Air Pollution
Neoplasms
cancer mortality
cohort study
Medicine
Humans
air pollutants
030212 general & internal medicine
Lung cancer
Child
0105 earth and related environmental sciences
Aged
Aged, 80 and over
Bladder cancer
business.industry
lcsh:R
Public Health, Environmental and Occupational Health
Cancer
Infant
Environmental Exposure
Middle Aged
medicine.disease
meta-analysis
Meta-analysis
Child, Preschool
Female
Particulate Matter
business
Liver cancer
Kidney cancer
Cohort study
Subjects
Details
- Language :
- English
- ISSN :
- 16604601
- Volume :
- 15
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- International Journal of Environmental Research and Public Health
- Accession number :
- edsair.doi.dedup.....4e28eb587ed23fa41862db9912a0579f