Cerebrospinal Fluid Iron‐Ferritin Ratio as a Potential Progression Marker for Parkinson's Disease

Authors :: Inga Zerr
Fabian Maass
Paul Lingor
Bernhard Michalke
Sezgi Canaslan
Mathias Bähr
Matthias Schmitz
Desiree Willkommen
Source :: Movement disorders 36(12), 2967-2969 (2021). doi:10.1002/mds.28790
Publication Year :: 2021
Publisher :: Wiley, 2021.
Abstract: Longitudinal PD CSF samples were subjected to ICP-MS and the total amount of iron and other bioelements was quantified. Additionally, ferritin and protein biomarkers of neurodegeneration were measured. Over time, mean iron levels significantly increased while levels of ferritin decreased.

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