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A DNA walker powered by endogenous enzymes for imaging uracil-DNA glycosylase activity in living cells
- Source :
- Chemical Communications. 55:6026-6029
- Publication Year :
- 2019
- Publisher :
- Royal Society of Chemistry (RSC), 2019.
-
Abstract
- A DNA walker powered by endogenous enzymes is constructed. It performs automatic walking in living cells and can detect the uracil-DNA glycosylase activity in situ.
- Subjects :
- In situ
Metal Nanoparticles
010402 general chemistry
01 natural sciences
Catalysis
Flow cytometry
Automation
Cell Line, Tumor
DNA-(Apurinic or Apyrimidinic Site) Lyase
Materials Chemistry
Uracil-DNA glycosylase activity
medicine
Humans
heterocyclic compounds
A-DNA
Surface plasmon resonance
Uracil-DNA Glycosidase
Fluorescent Dyes
medicine.diagnostic_test
010405 organic chemistry
Chemistry
Optical Imaging
fungi
Metals and Alloys
food and beverages
DNA
General Chemistry
Surface Plasmon Resonance
Flow Cytometry
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Biochemistry
DNA glycosylase
Cell culture
Endogenous enzymes
Ceramics and Composites
Fluorescein
Gold
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....4dce9719db461d738415545e1125b441
- Full Text :
- https://doi.org/10.1039/c9cc01912j