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A case of intraparotid schwannoma in a juvenile: Clinical, pathological, ultrastructural, and immunohistopathological study, including an examination of Ki-67 and MCM-3 expressions
- Source :
- Ultrastructural Pathology. 40:222-228
- Publication Year :
- 2016
- Publisher :
- Informa UK Limited, 2016.
-
Abstract
- Pleomorphic adenoma, the most common benign nonvascular tumor of the parotid gland in juveniles, should be differentiated from other extremely rare tumors, including schwannoma. In this article, we present a rare case of an intraparotid schwannoma in a juvenile, along with the patient history, a description of pathological features, and the results of ultrastructural and immunohistochemical examination. The respective labeling indexes of Ki-67 and MCM-3, i.e., the mean proportions of positive tumor cells out of 1000 tumoral cells counted in 10 microscopic fields at ×400 magnification, given as a percentage, were found to be 0.82% and 0.4%, respectively.
- Subjects :
- Male
0301 basic medicine
Pathology
medicine.medical_specialty
Adolescent
Schwannoma
Pathology and Forensic Medicine
Pleomorphic adenoma
03 medical and health sciences
0302 clinical medicine
Microscopy, Electron, Transmission
stomatognathic system
Structural Biology
Biomarkers, Tumor
otorhinolaryngologic diseases
medicine
Humans
Juvenile
Pathological
biology
business.industry
Minichromosome Maintenance Complex Component 3
Anatomy
medicine.disease
Immunohistochemistry
Parotid Neoplasms
Parotid gland
stomatognathic diseases
Ki-67 Antigen
030104 developmental biology
medicine.anatomical_structure
030220 oncology & carcinogenesis
Ki-67
Ultrastructure
biology.protein
business
Neurilemmoma
Subjects
Details
- ISSN :
- 15210758 and 01913123
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Ultrastructural Pathology
- Accession number :
- edsair.doi.dedup.....4dc9899122ed2bd42e2edfc403fe5cae