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Liddle Syndrome: Clinical and Cellular Abnormalities
- Source :
- Hospital Practice. 29:95-105
- Publication Year :
- 1994
- Publisher :
- Informa UK Limited, 1994.
-
Abstract
- Clinical findings resemble those of primary hyperaldosteronism, except that aldosterone secretion is negligible. The fault appears to lie with continuously avid sodium channels in the distal nephron, resulting in excessive salt absorption, potassium wasting, and severe hypertension. Insights gained in this disorder may help clarify more common forms of low-renin hypertension.
- Subjects :
- Male
medicine.medical_specialty
Adolescent
Hypokalemia
Distal nephron
Sodium Channels
chemistry.chemical_compound
Internal medicine
medicine
Humans
Wasting
Aldosterone
business.industry
Sodium channel
Alkalosis
Syndrome
General Medicine
medicine.disease
Hyperaldosteronism
Pedigree
Liddle Syndrome
Endocrinology
chemistry
Hypertension
Female
medicine.symptom
business
Subjects
Details
- ISSN :
- 23771003 and 21548331
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Hospital Practice
- Accession number :
- edsair.doi.dedup.....4d78017a23218aea3f51df606d9b6c18