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Association of cardiac baroreflex sensitivity with blood pressure transients: influence of sex and menopausal status
- Source :
- Frontiers in Physiology, Vol 3 (2012), Frontiers in Physiology
- Publication Year :
- 2012
- Publisher :
- Frontiers Media S.A., 2012.
-
Abstract
- The magnitude of decrease in blood pressure (BP) during a vasoactive drug bolus may be associated with the calculated baroreflex sensitivity (BRS). The purpose of the present study was to evaluate whether sympathetic and/or cardiac BRS relates to the extent of change in BP and whether this was altered by sex hormones. Fifty-one young women (27 ± 1 years), 14 older women (58 ± 1 years), and 36 young men (27 ± 1 years) were studied. Heart rate, BP, and muscle sympathetic nerve activity (MSNA) were monitored. Sympathetic BRS was analyzed using the slope of the MSNA-diastolic blood pressure (DBP) relationship and cardiac BRS was analyzed using the R–R interval-systolic blood pressure (SBP) relationship. Young women and men had similar mean arterial pressures (MAP, 91 ± 1 vs. 90 ± 1 mmHg), cardiac BRS (19 ± 1 vs. 21 ± 2 ms/mmHg), and sympathetic BRS (−6 ± 1 vs. −7 ± 1 AU/beat/mmHg), respectively. Older women had higher MAP (104 ± 4 mmHg, p
- Subjects :
- medicine.medical_specialty
Aging
sympathetic nerve activity
Cardiac baroreflex
lcsh:QP1-981
Physiology
Female sex hormones
business.industry
fungi
cardiovagal
blood pressure regulation
Baroreflex
lcsh:Physiology
Bolus (medicine)
Blood pressure
Endocrinology
Physiology (medical)
Vasoactive
Internal medicine
Heart rate
medicine
business
Original Research
Hormone
Subjects
Details
- Language :
- English
- Volume :
- 3
- Database :
- OpenAIRE
- Journal :
- Frontiers in Physiology
- Accession number :
- edsair.doi.dedup.....4d70bd32e21d932e01e2a2e4a89b2a02