Additional file 1 of Association between early detected heart failure stages and future cardiovascular and non-cardiovascular events in the elderly (Copenhagen Heart Failure Risk Study)

Additional file 1: Table S1. Inclusion and exclusion criteria for study population. Table S2. Definition of abnormal echocardiographic parameters in the Copenhagen Heart Failure Risk Study. Abbreviations: LVEF, left ventricle ejection fraction; LV, left ventricle; LVEDV, left ventricle end-diastolic diameter volume; e���, myocardial peak early velocity; E, peak velocity of early mitral inflow; GLS, global longitudinal strain. Table S3. ICD codes used for outcomes and procedure codes. CABG, coronary artery bypass grafting; IHD, ischemic heart disease; PCI, percutaneous coronary intervention; ICD-10, 10th revision of the International Classification of Diseases system. Figure S1. a-d: Cumulative incidence curves for the individual outcomes of (a) HFH, (b) all-cause death, (c) stroke, and (d) IHD by HF stage. Total number of events were HFH: 14, IHD: 22, stroke: 18, all cause death: 29. HFH, heart failure hospitalization; IHD, Ischemic heart disease. Table S4. A Cox proportional-hazards model adjusted for age and gender to estimate the hazard rate ratio of the composite outcome. Results presented with 95% confidence intervals and p-value. Table S5. Cause of first non-CV hospitalization by HF stage in numbers and percentages by HF stage. Non-CV, non-cardiovascular.