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Supplemental Figure 2 from A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors

Supplemental Figure 2 from A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors

Authors :
Pablo Umaña
Christian Klein
Vaios Karanikas
Jose Saro
Christiane Jaeger
Thomas von Hirschheydt
Sebastian Neumann
Sherri Dudal
Nathalie Steinhoff
Valeria Nicolini
Mario Perro
Christian Gerdes
Annette Seidl
Teilo Schaller
Sandra Grau-Richards
Peter Bruenker
Oliver Ast
Ekkehard Moessner
Ralf J. Hosse
Thomas Hofer
Steffi Lehmann
Walter Bodmer
Djamila Ouaret
Tina Weinzierl
Sara Colombetti
Johannes Sam
Tanja Fauti
Marina Bacac
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Pharmacokinetic profiles of CEA TCB in mice, additional information on CD3 signaling, T cell activation, tumor cell lysis and cytokine release upon CEA TCB and untargeted control TCB treatment.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....4d25ab83b90dec4d79470db61b3ea72f
Full Text :
https://doi.org/10.1158/1078-0432.22456472