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Novel VIM metallo-beta-lactamase variant, VIM-24, from a Klebsiella pneumoniae isolate from Colombia

Authors :
Maria Camila, Montealegre
Adriana, Correa
David F, Briceño
Natalia C, Rosas
Elsa, De La Cadena
Sory J, Ruiz
Maria F, Mojica
Ruben Dario, Camargo
Ivan, Zuluaga
Adriana, Marin
John P, Quinn
Maria Virginia, Villegas
Luis, Gonzalez
Source :
Antimicrobial agents and chemotherapy. 55(5)
Publication Year :
2011

Abstract

We report the emergence of a novel VIM variant (VIM-24) in a Klebsiella pneumoniae isolate in Colombia. The isolate displays MICs for carbapenems below the resistance breakpoints, posing a real challenge for its detection. The bla VIM-24 gene was located within a class 1 integron carried on a large plasmid. Further studies are needed to clarify its epidemiological and clinical impact.

Details

ISSN :
10986596
Volume :
55
Issue :
5
Database :
OpenAIRE
Journal :
Antimicrobial agents and chemotherapy
Accession number :
edsair.doi.dedup.....4d233792975bebf863f9270b7282b44e